{"id":158653,"date":"2023-09-21T21:03:45","date_gmt":"2023-09-21T21:03:45","guid":{"rendered":"https:\/\/tecscience.tec.mx\/en\/?p=158653"},"modified":"2024-12-10T17:25:21","modified_gmt":"2024-12-10T23:25:21","slug":"regeneron-genetics-and-tec-de-monterrey","status":"publish","type":"post","link":"https:\/\/tecscience.tec.mx\/en\/health\/regeneron-genetics-and-tec-de-monterrey\/","title":{"rendered":"An alliance Between Regeneron Genetics and Tec Will Boost Knowledge of Mexican Genome"},"content":{"rendered":"\n<p><strong>Tecnol\u00f3gico de Monterrey<\/strong> and <a href=\"https:\/\/www.regeneron.com\/science\/genetics-center\">Regeneron Genetics Center<\/a> have signed a collaboration agreement that will promote the scope and objectives of the <a href=\"https:\/\/content.tecsalud.mx\/proyectoorigen\">oriGen project<\/a>, which aims to collect and expand the understanding of the genetic information of the Mexican population and accelerate research advances in health.<\/p>\n\n\n\n<p>This alliance enables the reviewing of exomes (small vesicles that allow cellular communication) from all the project samples, as well as <strong>sequencing the complete genome in the samples of 10,000 individuals<\/strong>, out of the 100,000 that are estimated to participate in the <a href=\"https:\/\/tecscience.tec.mx\/en\/interactives\/origen-project\/\" target=\"_blank\" rel=\"noreferrer noopener\">oriGen project<\/a>, which will allow analysis of the genetic characteristics from all the information collected.<\/p>\n\n\n\n<p>During the event, <strong>David Garza<\/strong>, Rector and Executive President of Tec de Monterrey, said that we are experiencing a \u201csea change\u201d with the incorporation of new health and genomics infrastructure.<\/p>\n\n\n\n<p>\u201cI believe that we are facing what some call a sea change, a change of era. That change needs someone dynamic who says &#8216;I&#8217;m going to participate in the construction of that infrastructure.&#8217; I&#8217;m pleased that Tec de Monterrey, in synergy with Regeneron, is the protagonist of this new era, of a new milestone such as the <a href=\"https:\/\/tecscience.tec.mx\/es\/tag\/proyecto-origen\/\" target=\"_blank\" rel=\"noreferrer noopener\">oriGen project<\/a>.\u201d<\/p>\n\n\n\n<p><strong>Guillermo Torre<\/strong>, Rector of <a href=\"https:\/\/content.tecsalud.mx\/proyectoorigen\" target=\"_blank\" rel=\"noreferrer noopener\">TecSalud<\/a> and Vice President of Research at Tecnol\u00f3gico de Monterrey, mentioned that projects like this become important because &#8220;they highlight the capacity of Mexican scientists and secondly, because they show the relevance of applied research for the benefit of Mexicans.&#8221;<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"OriGen: the search for the Mexican genome\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/vFY-gtHQlpo?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-higher-incidence-of-diabetes-and-obesity-in-the-mexican-population\"><strong>Higher incidence of diabetes and obesity in the Mexican population<\/strong><\/h2>\n\n\n\n<p>According to <a href=\"https:\/\/tecscience.tec.mx\/en\/health\/pablo-kuri\/\">Pablo Kuri<\/a>, leader of oriGen, the project will become the country&#8217;s <strong>repository of genetic and epidemiological information<\/strong> and \u2212with the collaboration of other centers such as Regeneron Genetics Center\u2212 \u201cwe hope to have an <strong>improvement in the health of the Mexican population<\/strong> in the end. That&#8217;s what we all want.&#8221;<\/p>\n\n\n\n<p>Less than a year after the launch of the project, more than 20,000 people have participated and more than 1,500 complete genomes have been sequenced in states such as Mexico City, Nuevo Le\u00f3n, Coahuila, Durango, and Tamaulipas.<\/p>\n\n\n\n<p>Among the first results that the analyses have yielded is that <strong>25% of the population has been diagnosed with diabetes<\/strong>, contrary to data from the National Health and Nutrition Survey (ENSANUT, in Spanish), which reported 10.2%.<\/p>\n\n\n\n<p>They also found an <strong>obesity rate of 47.4%<\/strong>, compared to data from the World Health Organization (WHO) that reported 36%.<\/p>\n\n\n\n<p>Some of the challenges that the project presents so far are reaching 100,000 participants before 2025, since elections are approaching and the sociopolitical environment may delay sampling,<\/p>\n\n\n\n<p>In addition, it currently presents various biases, including one for sex, with a 2:1 ratio of women to men, as well as an underrepresentation of younger age groups, with the greatest number of participants being the elderly.<\/p>\n\n\n\n<p><strong>\u201cOur young people don&#8217;t want to participate, which is unfortunate,\u201d<\/strong> Kuri said. \u201cWe are making an effort to correct this as we move forward.\u201d<\/p>\n\n\n\n<p>Also, it was recognized that the project, conceived five years ago, is a sign of the intention to do applied science that really drives change in the population.<\/p>\n\n\n\n<p>Gon\u00e7alo Abecasis, Vice President and Director of Data Science Genomics at Regeneron Genetics Center, described it as \u201cfundamental\u201d to understand the genetic characteristics of each population in the world, in order to focus medical efforts on their vulnerabilities and predispositions.<\/p>\n\n\n\n<p>\u201cThere are many things about the health of people in Mexico that you could never learn from studying other populations in the world,\u201d he said.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-regeneron-genetics-center\"><strong>What is Regeneron Genetics Center?<\/strong><\/h2>\n\n\n\n<p>Regeneron Genetics Center is a wholly owned subsidiary of Regeneron Pharmaceuticals, which focuses on early gene discovery and functional genomics.<\/p>\n\n\n\n<p>The primary goal of RGC is to improve patient outcomes with new drugs, clinical indications for development programs, and genomic biomarkers for pharmacogenomic applications. It has presence in 17 countries.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The university has signed an agreement with the international company that will help it to analyze genetic samples.<\/p>\n","protected":false},"author":12,"featured_media":158657,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","footnotes":""},"categories":[86],"tags":[224,143,144],"class_list":["post-158653","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-health","tag-origen-project","tag-tecsalud"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.0 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Agreement Between Regeneron Genetics and Tec Will Boost Knowledge of Mexican Genome | TecScience<\/title>\n<meta name=\"description\" content=\"The university has signed an agreement with the international company that will help it to analyze the genetic samples.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tecscience.tec.mx\/en\/health\/regeneron-genetics-and-tec-de-monterrey\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"An alliance Between Regeneron Genetics and Tec Will Boost Knowledge of Mexican Genome\" \/>\n<meta property=\"og:description\" content=\"The university has signed an agreement with the international company that will help it to analyze the genetic samples.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tecscience.tec.mx\/en\/health\/regeneron-genetics-and-tec-de-monterrey\/\" \/>\n<meta property=\"og:site_name\" content=\"TecScience\" \/>\n<meta property=\"article:published_time\" 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Creo que la ciencia, al fomentar el pensamiento cr\u00edtico, puede empoderar a la humanidad y, al ser la base de los avances tecnol\u00f3gicos, puede ayudarla a vivir en las mejores condiciones posibles.","url":"https:\/\/tecscience.tec.mx\/en\/author\/igutierrez\/"}]}},"_links":{"self":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts\/158653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/comments?post=158653"}],"version-history":[{"count":0,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts\/158653\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/media\/158657"}],"wp:attachment":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/media?parent=158653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/categories?post=158653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/tags?post=158653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}