{"id":162595,"date":"2024-05-28T14:05:30","date_gmt":"2024-05-28T20:05:30","guid":{"rendered":"https:\/\/tecscience.tec.mx\/en\/?p=162595"},"modified":"2024-12-10T17:10:45","modified_gmt":"2024-12-10T23:10:45","slug":"flirt","status":"publish","type":"post","link":"https:\/\/tecscience.tec.mx\/en\/health\/flirt\/","title":{"rendered":"FLiRT, The New Strains of Covid-19 that Trigger Alerts in the United States"},"content":{"rendered":"\n<p><strong>SARS-CoV-2<\/strong>, the coronavirus causing <strong><a href=\"\/en\/tag\/covid-19\/\" target=\"_blank\" rel=\"noreferrer noopener\">Covid-19<\/a><\/strong>, which triggered the global pandemic of 2020, continues to mutate and its latest variants have alerted US health authorities, but what do we know about the <strong>new strains<\/strong>, known as <strong>FLiRT<\/strong>?<\/p>\n\n\n\n<p>\u201cTo better understand how the <strong>FLiRT<\/strong> strains emerged, it might help to see how the SARS-CoV-2 virus has changed over time, with new variants forming as mutations emerged in its genetic code\u201d, says Yale University in a text <a href=\"https:\/\/www.yalemedicine.org\/news\/3-things-to-know-about-flirt-new-coronavirus-strains\" target=\"_blank\" rel=\"noreferrer noopener\">published on its website<\/a>.<\/p>\n\n\n\n<p>\u200b\u200bAccording to the text, <strong>Omicron<\/strong> was a variant of SARS-CoV-2 that took hold in the US in <strong>2021<\/strong> and began to spawn subvariants of its own. One of those was <strong><a href=\"https:\/\/conecta.tec.mx\/es\/noticias\/nacional\/salud\/sintomas-y-rasgos-de-la-nueva-subvariante-de-covid-jn1-pirola\" target=\"_blank\" rel=\"noreferrer noopener\">JN.1<\/a><\/strong>, which was identified in September <strong>2023<\/strong> and spread through the country during the winter months, leading to a spike in Covid-19 hospitalizations.<\/p>\n\n\n\n<p>Yale Medicine explains that JN.1 also has descendants; the <strong>FLiRT subvariants<\/strong> are spinoffs of one called <strong>JN.1.11.1<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Hablemos de: #Coronavirus\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/qp5t5EPTwws?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What Are the FLiRT Strains And Where Did They Come From?<\/strong><\/h2>\n\n\n\n<p>We know that <strong>FLiRTs<\/strong> come from the <strong>Omicron <\/strong>variant, specifically <strong>JN.1.11.1<\/strong>, and have <strong>two mutations<\/strong> in their spike proteins (the protrusions on the surface of the virus) that weren&#8217;t seen in JN.1.<\/p>\n\n\n\n<p>\u201c<strong>FLiRT<\/strong> is the term being used to describe a <strong>whole family of different variants<\/strong>\u2014including <strong>KP.2<\/strong>, <strong>JN.1.7<\/strong>, and any other variants starting with <strong>KP<\/strong> or <strong>JN<\/strong>\u2014that appear to have independently picked up the same set of mutations. This is called convergent evolution\u201d, mentions an article published by Johns Hopkins University.<\/p>\n\n\n\n<p>Nobody knows exactly where the <strong>FLiRT<\/strong> variants first emerged, but the US Centers for Disease Control and Prevention (CDC) first detected these strains in <a href=\"\/en\/biotechnology\/a-new-opportunity-for-alzheimers-detection\/\" target=\"_blank\" rel=\"noreferrer noopener\">wastewater<\/a> and have since been identified in other countries such as Canada and the United Kingdom.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Why Are FLiRT Strains Of Concern To the US?<\/strong><\/h2>\n\n\n\n<p>On March 13, Johns Hopkins University <a href=\"https:\/\/publichealth.jhu.edu\/2024\/what-to-know-about-covid-flirt-variants\" target=\"_blank\" rel=\"noreferrer noopener\">published<\/a>: \u201cAt the end of March, the <strong>KP.2<\/strong> variant was causing about 4% of infections in the U.S., according to the CDC, while its parental strain, <strong>JN.1<\/strong>, was causing over 50% of infections at that time. As of early May, <strong>KP.2 <\/strong>makes up about 28% of infections, overtaking <strong>JN.1<\/strong> as the dominant variant\u201d.<\/p>\n\n\n\n<p>The latest <a href=\"https:\/\/covid.cdc.gov\/covid-data-tracker\/#variant-proportions\" target=\"_blank\" rel=\"noreferrer noopener\">data from the Centers for Disease Control and Prevention<\/a>, which cut information from <strong>11 to 25 May<\/strong>, show that in a week the variant <strong>KP.2<\/strong> went from <strong>20.5%<\/strong> to <strong>28.5%<\/strong> of infections.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><picture>\r\n                <source srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US-1024x543.webp\" type=\"image\/webp\">\r\n                <img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"543\" src=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US-1024x543.png\" alt=\"\" class=\"wp-image-162600\" srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US-1024x543.png 1024w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US-300x159.png 300w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US-768x407.png 768w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US-1536x815.png 1536w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-KP.2-US.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\r\n            <\/picture><figcaption class=\"wp-element-caption\">This graph shows the advance of the KP.2 variant during recent weeks in the United States. (Photo: CDC)<\/figcaption><\/figure>\n\n\n\n<p>The prevalence of this variant comes at a critical time, when experts are deciding how to formulate <strong>Covid-19 vaccines<\/strong> for next fall.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Will FLiRT Affect Vaccine Formulation?<\/strong><\/h2>\n\n\n\n<p>Andy Pekosz, professor of Microbiology and Molecular Immunology at Johns Hopkins, said in an interview posted on the University&#8217;s website that \u201clast year, <a href=\"\/en\/health\/do-we-need-to-get-vaccinated-against-covid-19-again\/\" target=\"_blank\" rel=\"noreferrer noopener\">vaccines were based on the <strong>XBB.1.5<\/strong> variant and, just a few months later, the <strong>JN.1<\/strong> variant became the dominant variant in the US<\/a>\u201d.<\/p>\n\n\n\n<p>So, \u201cnew <strong>Covid variants<\/strong> are likely to crop up after a decision is made \u2014just as it did last summer\u2014 but the goal remains to <strong>select a formulation<\/strong> that, come fall, will <strong>match the circulating variants as closely as possible<\/strong>\u201d.<\/p>\n\n\n\n<p>The academic explained that it&#8217;s during this month that governing bodies such as the World Health Organization (WHO) and the United States Food and Drug Administration (FDA) recommend an updated formulation for <strong>Covid-19 vaccines<\/strong>, which are launched early fall because winter is when cases rebound.<\/p>\n\n\n\n<p>\u201cAt the end of April, the WHO announced that their Covid vaccine advisory group advises using the <strong>JN.1 lineage<\/strong> as the antigen for the upcoming formulations of the vaccine. All of these <strong>FLiRT variants<\/strong> are within the <strong>JN.1 <\/strong>family of variants\u201d, Pekosz said.<\/p>\n\n\n\n<p>\u201cHere in the US, the <strong>FDA<\/strong> has postponed its meeting to determine the fall 2024 Covid vaccine from mid-May to early June. That gives them more time to see which of the <strong>FLiRT<\/strong> variants is becoming the dominant one so they can fine-tune the WHO recommendation to what they anticipate will be most prominent in the fall\u201d, he added.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-spotify wp-block-embed-spotify wp-embed-aspect-21-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Spotify Embed: Ep. 58 - Cuando no te recuperas de COVID\" style=\"border-radius: 12px\" width=\"100%\" height=\"152\" frameborder=\"0\" allowfullscreen allow=\"autoplay; clipboard-write; encrypted-media; fullscreen; picture-in-picture\" loading=\"lazy\" src=\"https:\/\/open.spotify.com\/embed\/episode\/1qp7vUbeiBgKAyfCk6j9ul?si=PAdH-riGT-Snitm_d6iSWA&#038;utm_source=oembed\"><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What Are the Symptoms of FLiRT and How to Protect Yourself?<\/strong><\/h2>\n\n\n\n<p>Experts from Johns Hopkins and Yale point out that the <strong>symptoms <\/strong>aren&#8217;t different from those presented in other variants, \u201cwe continue to see more mild disease, but that\u2019s likely not because the virus is milder, but because our immunity is so much stronger now. After years of <strong>vaccinations and infections<\/strong>, most of the population is better able to fight off an infection without as much concern for severe disease\u201d.<\/p>\n\n\n\n<p>The period of infection of <strong>FLiRT <\/strong>remains the same as that of <strong>JN.1<\/strong> and the previous<strong> Omicron <\/strong>variants. Likewise, antivirals such as Paxlovid are still the most recommended drugs for high-risk people because they still work against the variant JN.1.<\/p>\n\n\n\n<p>Some of the recommendations are:&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Have rapid tests at home, in case symptoms occur\u00a0<\/li>\n\n\n\n<li>Be aware of local health authorities<\/li>\n\n\n\n<li>Make meetings in ventilated areas<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>In the month that WHO and FDA decide on the formulation of vaccines for the fall, cases of the new variant rebound.<\/p>\n","protected":false},"author":41,"featured_media":162604,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","footnotes":""},"categories":[86],"tags":[169,224],"class_list":["post-162595","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-covid-19","tag-health"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.0 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What do we know about FLiRT, the new strains of Covid-19? | TecScience<\/title>\n<meta name=\"description\" content=\"The new FLiRT variant triggers alerts in the United States about the increase in the number of cases. It accounts for 30% of infections.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tecscience.tec.mx\/en\/health\/flirt\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FLiRT, The New Strains of Covid-19 that Trigger Alerts in the United States\" \/>\n<meta property=\"og:description\" content=\"The new FLiRT variant triggers alerts in the United States about the increase in the number of cases. 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It accounts for 30% of infections.","breadcrumb":{"@id":"https:\/\/tecscience.tec.mx\/en\/health\/flirt\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/tecscience.tec.mx\/en\/health\/flirt\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/tecscience.tec.mx\/en\/health\/flirt\/#primaryimage","url":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-covid-19.jpg","contentUrl":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2024\/05\/flirt-covid-19.jpg","width":750,"height":500,"caption":"The KP.2 variant, belonging to the new FLiRT strains, has gone from 4% of infections in the US in March to 28.5% in the last two weeks of May. 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