{"id":169462,"date":"2025-05-02T18:28:26","date_gmt":"2025-05-03T00:28:26","guid":{"rendered":"https:\/\/tecscience.tec.mx\/en\/?p=169462"},"modified":"2025-05-02T18:29:56","modified_gmt":"2025-05-03T00:29:56","slug":"solutions-for-heart-problems","status":"publish","type":"post","link":"https:\/\/tecscience.tec.mx\/en\/industrial-transformation\/solutions-for-heart-problems\/","title":{"rendered":"New Frontiers in Treating Obesity: Mexican Scientists Explore CBD, Chickpeas, and Nanotechnology"},"content":{"rendered":"\n<p>At the <a href=\"\/en\/tag\/international-conference-on-obesity-research-2025\/\" target=\"_blank\" rel=\"noreferrer noopener\">2025 International Obesity Research Congress<\/a>, researchers from the <a href=\"\/en\/tag\/institute-for-obesity-research\/\" target=\"_blank\" rel=\"noreferrer noopener\">Institute for Obesity Research (IOR)<\/a> unveiled a series of breakthroughs to transform how we treat obesity and its far-reaching effects, especially on heart health. Their work includes potential therapies for cardiac hypertrophy, arrhythmias, and blood sugar spikes, using tools like bioengineering, cellular models, and plant-derived compounds like cannabidiol.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"\u00bfDe qu\u00e9 trata el Congreso Internacional de Investigaci\u00f3n sobre Obesidad 2025?\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/YqVC4Q339yE?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Using CBD to Counter Cardiac Hypertrophy<br><\/strong><\/h2>\n\n\n\n<p><strong><a href=\"https:\/\/mx.linkedin.com\/in\/lautaro-daniel-fabiani-442717223\" target=\"_blank\" rel=\"noreferrer noopener\">Lautaro Daniel Fabiani<\/a><\/strong> presented promising results from his work with cannabidiol (CBD), the non-psychoactive component of cannabis, to counteract cardiac hypertrophy\u2014an <strong>abnormal enlargement of the heart muscle<\/strong>.<\/p>\n\n\n\n<p>In both animal and cell models, administering different doses of CBD significantly reduced the size of hypertrophic heart cells. Fabiani\u2019s team also saw a decline in molecular markers associated with tissue damage and fibrosis. In short, CBD prevented cells from growing excessively and helped keep heart tissue more elastic and functional.<\/p>\n\n\n\n<p>\u201cWe can say with confidence that CBD effectively reduces cardiac hypertrophy and the molecular signs of tissue remodeling,\u201d Fabiani explained.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Targeting Mitochondrial Calcium to Prevent Arrhythmias<br><\/strong><\/h2>\n\n\n\n<p>Felipe Salazar introduced research on mitochondrial function and its role in cardiac arrhythmias, potentially life-threatening conditions like ventricular fibrillation. His team focused on a specific calcium channel, the mitochondrial calcium uniporter (MCU), which regulates how calcium flows into mitochondria.<\/p>\n\n\n\n<p>Too much calcium inside mitochondria can trigger oxidative stress and disrupt the heart\u2019s rhythm. Using a targeted MCU inhibitor, the researchers prevented 100% of arrhythmias in experimental models simulating extreme heart stress.<\/p>\n\n\n\n<p>\u201cMitochondrial calcium overload leads to oxidative stress that affects not just the mitochondria but also the sarcoplasmic reticulum,\u201d Salazar said. \u201cInhibiting this channel may offer a new way to preserve cellular energy and prevent arrhythmias.\u201d<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><picture>\r\n                <source srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2-1024x1024.webp\" type=\"image\/webp\">\r\n                <img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2-1024x1024.jpg\" alt=\"\" class=\"wp-image-169469\" srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2-1024x1024.jpg 1024w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2-300x300.jpg 300w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2-150x150.jpg 150w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2-768x768.jpg 768w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2025\/05\/what-is-rna-2.jpg 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\r\n            <\/picture><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Chickpea-Based Beverage May Help Curb Blood Sugar Spikes<br><\/strong><\/h2>\n\n\n\n<p><a href=\"https:\/\/mx.linkedin.com\/in\/frineth-lim%C3%B3n-4a09b816b\" target=\"_blank\" rel=\"noreferrer noopener\">Frineth de la Luz Lim\u00f3n<\/a> presented an experimental drink made from selenium-enriched sprouted chickpea flour. The beverage is designed to increase satiety and reduce glucose spikes, key contributors to metabolic diseases.<\/p>\n\n\n\n<p>The researchers found that the powdered drink with finer particle sizes contained more protein, fat, and beneficial fatty acids. These characteristics slowed digestion in lab simulations and reduced the glycemic impact, hinting at a promising tool in the fight against chronic disease.<\/p>\n\n\n\n<p>\u201cThe slowly digestible starch content was higher in the filtered versions of the drink,\u201d said Lim\u00f3n. \u201cThat suggests a <strong>lower glycemic response and potential protective effects<\/strong>.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Nanoparticles That Target Fat Cells<br><\/strong><\/h2>\n\n\n\n<p><a href=\"https:\/\/mx.linkedin.com\/in\/aneliza-flores-villarreal-5b0a581b2\">Aneliza Flores<\/a> shared early findings from a nanotechnology project to deliver treatments directly to white adipose tissue\u2014the fat cells that store excess energy.<\/p>\n\n\n\n<p>Her team developed polymeric nanoparticles engineered to recognize a specific protein on fat cells and deliver therapeutic agents like CBD. In lab tests, they achieved a 26% increase in the particles\u2019 ability to bind with target cells, thanks to surface modifications that boost interaction with fat tissue.<\/p>\n\n\n\n<p>\u201cWe\u2019ve optimized the concentrations,\u201d Flores said. \u201cNow we\u2019re planning additional in vitro studies to test cytotoxicity using encapsulated cannabidiol.\u201d<\/p>\n\n\n\n<p>From chickpeas to cannabinoids, and from nanotech to heart cells, these studies reflect a growing movement to treat obesity with nuance and scientific rigor. Rather than focusing solely on weight, these researchers are asking bigger questions\u2014about how we heal, prevent, and care.<\/p>\n\n\n\n<p><strong><em>Were you interested in this story? Do you want to publish it? Contact our content editor to learn more about&nbsp;<\/em><\/strong><strong><em><a target=\"_blank\" href=\"mailto:marianaleonm@tec.mx\" rel=\"noreferrer noopener\">marianaleonm@tec.mx<\/a><\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>At the Institute for Obesity Research, teams of scientists are developing innovative therapies for obesity-related conditions\u2014going far beyond fat loss to tackle cardiovascular issues at the molecular level.<\/p>\n","protected":false},"author":47,"featured_media":169470,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","footnotes":""},"categories":[557],"tags":[166,385,563,564],"class_list":["post-169462","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industrial-transformation","tag-institute-for-obesity-research","tag-international-conference-on-obesity-research","tag-international-conference-on-obesity-research-2025","tag-tec-talk"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.0 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>New Frontiers in Treating Obesity: Mexican Scientists Explore CBD, Chickpeas, and Nanotechnology | TecScience<\/title>\n<meta name=\"description\" content=\"At the Institute for Obesity Research, teams of scientists are developing 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