{"id":169463,"date":"2025-05-02T15:34:27","date_gmt":"2025-05-02T21:34:27","guid":{"rendered":"https:\/\/tecscience.tec.mx\/en\/?p=169463"},"modified":"2025-05-02T16:02:12","modified_gmt":"2025-05-02T22:02:12","slug":"the-hidden-power-of-vitamins-can-they-help-prevent-obesity-and-its-complications","status":"publish","type":"post","link":"https:\/\/tecscience.tec.mx\/en\/health\/the-hidden-power-of-vitamins-can-they-help-prevent-obesity-and-its-complications\/","title":{"rendered":"The Hidden Power of Vitamins: Can They Help Prevent Obesity and Its Complications?"},"content":{"rendered":"\n<p>Although they often go unnoticed, vitamins are essential for keeping the body running smoothly. Nowadays, <a href=\"\/es\/salud\/ninos-en-mexico-no-comen-verduras-y-frutas\/\" target=\"_blank\" rel=\"noreferrer noopener\">our lifestyle and eating habits tend<\/a> to leave them out\u2014and that can come with consequences.<\/p>\n\n\n\n<p>A recent<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38084629\/\" target=\"_blank\" rel=\"noreferrer noopener\"> study on rats fed a \u201ccafeteria diet\u201d<\/a>\u2014high in fats, sugars, and calories, much like typical junk food\u2014found that supplementing with a commercial multivitamin reduced the levels of pro-inflammatory cytokines in the blood (molecules that promote inflammation and circulate in the bloodstream). So explained <a href=\"https:\/\/scholar.google.com\/citations?user=ZEgGPdAAAAAJ&amp;hl=es\" target=\"_blank\" rel=\"noreferrer noopener\">Jos\u00e9 Antonio Palma Jacinto<\/a>, one of the authors of the study <em><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11216102\/\" target=\"_blank\" rel=\"noreferrer noopener\">Putative mechanism of a multivitamin treatment against insulin resistance.<\/a><\/em><\/p>\n\n\n\n<p>Previous studies had already shown that certain <a href=\"\/en\/health\/vitamin-b12-baby\/\" target=\"_blank\" rel=\"noreferrer noopener\">vitamins<\/a>\u2014such as B2, B3, B5, B6, B7, B12, C, D, and E\u2014<strong>can help lower insulin resistance<\/strong>, a condition that prevents the body from using insulin effectively and is linked to diseases like type 2 diabetes. However, until now, the underlying mechanism behind this effect remained unclear.<\/p>\n\n\n\n<p>Using both<em> in vitro and in vivo<\/em> models (the former done in a lab using cells or tissues in a dish, the latter conducted in living organisms like animals), the study pinpointed two key factors: oxidative stress and lipoinflammation.<\/p>\n\n\n\n<p>These two processes, which often occur simultaneously, may contribute to the onset of insulin resistance during obesity\u2014and eventually to conditions such as type 2 diabetes, metabolic syndrome, or metabolic dysfunction-associated fatty liver disease.<\/p>\n\n\n\n<p>\u201cThese two factors\u2014oxidative stress and lipoinflammation\u2014<strong>are emerging as potential therapeutic targets<\/strong> for treating obesity and its complications, or even for developing preventive treatments,\u201d said Palma Jacinto during a brief talk as part of the <strong>Flash Tec Talks<\/strong> held at the <a href=\"http:\/\/en\/tag\/international-conference-on-obesity-research-2025\/\" target=\"_blank\" rel=\"noreferrer noopener\">2025 International Obesity Research Congress<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"\u00bfQu\u00e9 soluciones promete la ciencia del futuro para combatir la obesidad infantil?\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/LlMveyHoqk8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">How do these vitamins interact in the context of preventive treatment?<\/h2>\n\n\n\n<p>This multidisciplinary research suggests that certain vitamins may act at different molecular levels to reduce insulin resistance, primarily by regulating pathways associated with oxidative stress. The study evaluated the effect of 11 vitamins on key mechanisms tied to inflammation and antioxidant activity.<\/p>\n\n\n\n<p>\u201cUp to now, most reports have looked at the effects of individual vitamin administration, and those studies have shown that they can partially reduce the inflammatory state\u2014especially those vitamins with antioxidant properties,\u201d he noted.<\/p>\n\n\n\n<p>The researchers also used computer simulations to analyze how these vitamins interact with specific proteins, which could help explain the mechanisms documented in scientific literature.<\/p>\n\n\n\n<p>Palma Jacinto explained that the goal of this research is to better understand how certain vitamins might interact to serve as a preventive treatment for obesity-related diseases. These vitamins are being tested both in lab experiments and in living organisms.<\/p>\n\n\n\n<p>He stressed how crucial it is, before moving into preclinical in vivo studies, to clearly identify the target sites through which these vitamins act.<\/p>\n\n\n\n<p>\u201cIn some of the targets we&#8217;ve identified, we can see that in the mechanism promoted by the obesogenic environment\u2014broadly speaking\u2014vitamins would need to act at one of these levels to inhibit the inflammatory cascade,\u201d said the researcher, reflecting on the value of in silico studies to assess the binding affinity of these vitamins within the proposed mechanisms.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-spotify wp-block-embed-spotify wp-embed-aspect-21-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Spotify Embed: Ep. 115 - Experimentos con animales, \u00bfpuede la ciencia prescindir de ellos?\" style=\"border-radius: 12px\" width=\"100%\" height=\"152\" frameborder=\"0\" allowfullscreen allow=\"autoplay; clipboard-write; encrypted-media; fullscreen; picture-in-picture\" loading=\"lazy\" src=\"https:\/\/open.spotify.com\/embed\/episode\/3307Y31NXPs7M0eLxNyLJj?si=805d63a87fc748cb&#038;utm_source=oembed\"><\/iframe>\n<\/div><\/figure>\n\n\n\n<p><br><strong><em>Did you find this story interesting? Would you like to publish it? Contact our content editor to learn more at\u00a0<a href=\"mailto:marianaleonm@tec.mx\">marianaleonm@tec.mx<\/a>\u00a0<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jos\u00e9 Antonio Palma is researching how specific vitamins could help prevent obesity-related diseases\u2014such as insulin resistance\u2014by reducing inflammation and oxidative stress.<\/p>\n","protected":false},"author":42,"featured_media":169465,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","footnotes":""},"categories":[86],"tags":[385,563],"class_list":["post-169463","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-international-conference-on-obesity-research","tag-international-conference-on-obesity-research-2025"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.0 (Yoast SEO v27.5) - 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