{"id":172348,"date":"2026-02-03T14:22:08","date_gmt":"2026-02-03T20:22:08","guid":{"rendered":"https:\/\/tecscience.tec.mx\/en\/?p=172348"},"modified":"2026-02-11T09:37:08","modified_gmt":"2026-02-11T15:37:08","slug":"translational-oncology-from-lab-to-patient","status":"publish","type":"post","link":"https:\/\/tecscience.tec.mx\/en\/health\/translational-oncology-from-lab-to-patient\/","title":{"rendered":"Ethan Dmitrovsky and Translational Oncology: Bringing Science from the Lab to the Patient"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">From a refugee camp in Cambodia to leading the <a href=\"https:\/\/frederick.cancer.gov\/about\/leadership\/ethan-dmitrovsky\" target=\"_blank\" rel=\"noreferrer noopener\">Frederick National Laboratory for Cancer Research<\/a>, one of the world\u2019s most prestigious cancer research centers, <strong><a href=\"https:\/\/www.linkedin.com\/in\/ethan-dmitrovsky-md-b69038270\/\" target=\"_blank\" rel=\"noreferrer noopener\">Ethan Dmitrovsky<\/a>\u2019s career illustrates how translational oncology can turn scientific discoveries into real treatments for cancer patients.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A physician, scientist, and current director of the laboratory, Dmitrovsky\u2019s professional path bridges clinical experience, basic research, and strategic decision-making within institutions dedicated to global health and cancer research.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This vision was at the center of his conversation during the <strong><a href=\"https:\/\/congreso-estudiantil-nacional-de-investigacion-ceni.b12sites.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">International Congress on Educational Research (CENI)<\/a> at Tecnol\u00f3gico de Monterrey,<\/strong> a flagship event that brings together leaders in science, innovation, and education. During his keynote, Dmitrovsky explained that his scientific vocation emerged from a deep ethical conviction.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cMy motivation is deeply rooted in the concept of servant leadership,\u201d he said, referencing the ideas of Robert Greenleaf and emphasizing that research only finds its true meaning when it serves others.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For Dmitrovsky, research is not limited to generating technical knowledge or academic advances. His approach is grounded in a clear social responsibility: ensuring that science moves beyond the laboratory and has a direct impact on people\u2019s lives, particularly through the development of new strategies for <a href=\"https:\/\/tecscience.tec.mx\/en?s=cancer\">cancer treatment<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">From Clinical Experience to Translational Oncology<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One of the defining moments of his career occurred when, as a volunteer physician, he diagnosed leukemia in a child at a refugee camp. With no access to treatment, the disease was incurable.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That experience led him to question how cancer treatments were being developed. \u201cThat\u2019s when I realized we needed therapies that were less aggressive and more accessible\u2014treatments that could be applied anywhere in the world,\u201d he said. That realization set him on the path toward translational oncology: bringing discoveries from the lab into clinical practice.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"N\u00facleo de Investigaci\u00f3n de Impacto en Salud\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/yPhGLXVgGlI?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">The Challenge of Bringing Discoveries to Patients<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">For decades, cancer was viewed as a single disease. Today, that understanding has changed dramatically. \u201cWe used to define cancer by what it looked like under the microscope; now we know it is defined by its genetic profile,\u201d Dmitrovsky explained.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This shift opened the door to therapies that target specific mutations, transforming outcomes for many patients. These advances not only reshaped basic research but also changed how personalized treatments are designed. For Dmitrovsky, this is one of the main reasons for optimism in oncology today.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Still, many promising discoveries never become treatments. Dmitrovsky acknowledges that this gap remains one of the field\u2019s greatest challenges.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cHistorically, scientific research and clinical practice have not been as integrated as they should be,\u201d he said. The solution, he argues, lies in teams where scientists and physicians share responsibility for translating knowledge into clinical care.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Doing Science and Choosing What to Fund in Difficult Times<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Beyond the lab, Dmitrovsky has also played a key role in setting scientific priorities and deciding which projects receive funding. These decisions, he explained, are not based solely on academic metrics.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The central criteria include potential patient impact, methodological rigor, reproducibility, and teams\u2019 ability to work across disciplines. For him, funding science is also a way of shaping the future of research.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In a global context marked by budget cuts, misinformation, and political pressure, Dmitrovsky strongly defends the value of scientific research.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For him, doing science remains worthwhile because it represents a form of public service. Many of the answers to today\u2019s global health crises, he noted, emerged from decades of basic research that once seemed to have no immediate application.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Technologies Transforming Research<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Artificial intelligence (AI), big data analytics, computational biology, and gene editing are accelerating the pace of scientific discovery. Still, Dmitrovsky stressed that no technology can replace scientific judgment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The key, he said, is integrating these tools to ask better questions and make more informed decisions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">One of the central messages of his talk was directed at younger generations. For Dmitrovsky, scientific training must go beyond technical mastery.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cIt\u2019s not possible to be equally expert in both the clinic and the laboratory; you have to choose where you can make the greatest impact,\u201d he said. Even so, he emphasized the importance of understanding both worlds, as well as cultivating passion and perseverance.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><picture>\r\n                <source srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3-1024x1024.webp\" type=\"image\/webp\">\r\n                <img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3-1024x1024.png\" alt=\"\u201cIt\u2019s not possible to be equally expert in both the clinic and the laboratory; you have to choose where you can make the greatest impact.\u201d\nETHAN DMITROVSKY\nDirector of the Frederick National Laboratory for Cancer Research\" class=\"wp-image-172353\" style=\"width:657px;height:auto\" srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3-1024x1024.png 1024w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3-300x300.png 300w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3-150x150.png 150w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3-768x768.png 768w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/02\/QUOTES-WEB-DUPLICAR-3.png 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\r\n            <\/picture><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Leading Science Is More Than Managing It<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In Dmitrovsky\u2019s view, leading science requires vision, trust, and the ability to protect talent. It is not just about managing resources but about creating the conditions for knowledge to flourish. Many of the most complex barriers, he noted, are not technical but cultural\u2014and overcoming them requires conviction and collaboration.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Looking ahead, Dmitrovsky anticipates a future in which cancer research becomes increasingly personalized, interdisciplinary, and preventive.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For him, major breakthroughs will not come from isolated laboratories but from collaborative networks capable of integrating multiple disciplines and technologies around a shared purpose: improving patients\u2019 lives. His message is clear\u2014the future of cancer research will depend not only on technology but also on science\u2019s ability to collaborate, adapt, and remain committed to society.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em><strong>Did you find this story interesting? Would you like to publish it? Contact our content editor to learn more:\u00a0<a href=\"mailto:marianaleonm@tec.mx\" target=\"_blank\" rel=\"noreferrer noopener\">marianaleonm@tec.mx<\/a><\/strong><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The director of the Frederick National Laboratory for Cancer Research shares his vision of translational oncology, scientific leadership, and the future of cancer during his participation at Tec de Monterrey\u2019s CENI.<\/p>\n","protected":false},"author":57,"featured_media":172349,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","footnotes":""},"categories":[86],"tags":[224,138],"class_list":["post-172348","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-health","tag-school-of-medicine-and-health-sciences"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.0 (Yoast SEO v27.6) - 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