{"id":174860,"date":"2026-11-04T16:04:10","date_gmt":"2026-11-04T22:04:10","guid":{"rendered":"https:\/\/tecscience.tec.mx\/en\/?p=174860"},"modified":"2026-11-05T11:31:29","modified_gmt":"2026-11-05T17:31:29","slug":"organs-on-chips-to-understand-cancer-and-alzheimers","status":"publish","type":"post","link":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/","title":{"rendered":"Recreating Human Blood Vessels on a Chip to Understand Metastasis"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">How do cancer cells cross blood vessels during metastasis? What changes in the brain\u2019s protective barrier are linked to <a href=\"\/en?s=alzheimer\" target=\"_blank\" rel=\"noreferrer noopener\">Alzheimer\u2019s<\/a> disease? These are some of the questions researchers hope to answer using <a href=\"\/en\/biotechnology\/tumor-on-a-chip\/\" target=\"_blank\" rel=\"noreferrer noopener\">organ-on-a-chip<\/a> technology.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These tiny devices allow scientists to <strong>grow human cells under controlled laboratory conditions<\/strong>. Inside them, cells interact and organize themselves into structures that mimic those found in the human body, such as blood vessels, making it possible to study their behavior and natural properties.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/be.mit.edu\/faculty\/roger-d-kamm\/\" target=\"_blank\" rel=\"noreferrer noopener\">Roger Kamm<\/a>, a researcher in the Department of Biological Engineering at the <a href=\"\/en\/tag\/mit\/\" target=\"_blank\" rel=\"noreferrer noopener\">Massachusetts Institute of Technology<\/a> (MIT), presented his team\u2019s latest advances at the <a href=\"https:\/\/biofabrication2026.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">International Conference on Biofabrication 2026<\/a>, held at Tecnol\u00f3gico de Monterrey.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cWe let the cells do their own thing, interact with each other and develop the structures that are necessary to replicate what happens in vivo,\u201d he explained.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to Kamm, these models can be used by both academic researchers and pharmaceutical companies to test new treatments.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/kamm.webp\" alt=\"\" class=\"wp-image-174865\" srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/kamm.webp 750w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/kamm-300x200.webp 300w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/><figcaption class=\"wp-element-caption\">Roger Kamm, an MIT researcher, is developing organs-on-chips to study diseases and other biological processes. (Photo: Ricardo Trevi\u00f1o \/ TecScience)<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Recreating Human Tissues and Their Characteristics<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">To replicate the characteristics of human tissues, researchers use microfluidic technology, which controls the flow of liquids through tiny channels, while also harnessing natural processes such as cellular self-organization.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kamm\u2019s team is developing models in which human cells are placed inside a gel matrix that allows them to interact and organize themselves into <strong>three-dimensional structures<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researcher showed a video documenting the first 48 hours of an experiment in which endothelial cells, which line the inside of blood vessels, began connecting with one another to <strong>form small vascular networks<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cYou can see the endothelial cells are kind of reaching out, they find their neighbors, they form this nice three-dimensional structure,\u201d he explained. \u201cIf we wait a few more days, these become fully perfusible.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The team\u2019s goal was not simply to create these structures, but also to keep them functioning for extended periods, <strong>allowing researchers to study different biological processes<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers managed to <a href=\"https:\/\/www.nature.com\/articles\/s44341-025-00028-0\" target=\"_blank\" rel=\"noreferrer noopener\">keep the vascular networks intact for 51 days<\/a>, until they decided to end the experiment. \u201cThe flow turns out to be very important, not just for providing nutrients to the cells and oxygenation, but also in terms of stabilization of the vascular networks.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Studying the Spread of Cancer on Chips<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One of the applications Kamm presented focuses on studying <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42413554\/\" target=\"_blank\" rel=\"noreferrer noopener\">metastasis<\/a>, the process by which cancer cells break away from a primary tumor and spread to other parts of the body.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Using these models, the team investigated <strong>how certain tumor cells enter blood vessels, travel through the bloodstream, and cross vessel walls<\/strong> to reach other tissues.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kamm showed experiments in which cancer cells became trapped in capillaries, the smallest blood vessels in the body. While some managed to squeeze through the vessel walls, <strong>others were damaged by the forces generated by fluid flow<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In one example, a tumor cell extended part of its structure, latched onto the membrane surrounding the vessel, and <strong>created an opening to slip between two endothelial cells<\/strong>. Once the cancer cell had passed through, the gap closed again. Kamm explained that the entire process was captured on video over a four-hour period.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cWe can observe this, we can quantify it, we can study it under various perturbation conditions, but we can do this all in vitro,\u201d he emphasized.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><picture>\r\n                <source srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/Roer-Kamm.webp\" type=\"image\/webp\">\r\n                <img decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/Roer-Kamm.jpg\" alt=\"\" class=\"wp-image-174866\" srcset=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/Roer-Kamm.jpg 750w, https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/Roer-Kamm-300x200.jpg 300w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/>\r\n            <\/picture><figcaption class=\"wp-element-caption\">Kamm\u2019s research group focuses on five major areas: biological machines and microfluidics; angiogenesis and vasculogenesis; neurological diseases; cancer; and simulation and modeling. (Photo: MIT Department of Biological Engineering)<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Recreating Alzheimer\u2019s-Related Changes on Chips<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Another application developed by Kamm\u2019s team focuses on studying Alzheimer\u2019s disease. These models replicate key features of the blood-brain barrier, <strong>a structure that protects the brain and regulates the movement of substances<\/strong> between the bloodstream and brain tissue.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers <strong>grew nerve cells carrying genetic alterations associated with Alzheimer\u2019s and observed how they interacted with vascular networks<\/strong> created in the laboratory.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">After four weeks, they found increased accumulation of beta-amyloid, a <strong>protein linked to the disease<\/strong>, both in the nerve tissue and around the blood vessels. They also observed that the barrier had become more permeable, meaning substances could pass through it more easily.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In a more recent version of the model, a single genetic alteration was enough to produce substantial differences. For example, permeability increased to more than twice that of the control model.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cWe really didn\u2019t expect to see phenotypic changes in the system with just the single mutation. But in fact we do. They\u2019re very significant,\u201d Kamm explained.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researcher emphasized that these experiments make it possible to study how Alzheimer\u2019s may affect the structures that protect the brain and investigate the mechanisms underlying the disease.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Recreating the Journey of Drugs on Chips<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">By replicating key features of human tissues, the organs-on-chips developed by Kamm\u2019s team also offer an alternative for <strong>the pharmaceutical industry to test new drugs<\/strong>. At the same time, they could help reduce the need for animal testing.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThis has been motivated not only by the fact that we\u2019d like to preserve the welfare of animals, but also that nonhuman models really are not very good predictors of human disease,\u201d he noted.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For this ongoing research, the team created three models that replicate features of blood vessels, the lymphatic system, and the tissues surrounding cells. Using these models, researchers are studying how monoclonal antibodies, a type of medication used to treat various diseases, are absorbed when administered through injections under the skin, and how much of the drug ultimately reaches the bloodstream.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The results are combined with computational models and an artificial intelligence (AI) system designed to predict how much of a drug will reach the bloodstream.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Biofabrication 2026 Comes to Latin America for the First Time<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The 2026 International Conference on Biofabrication is taking place November 2\u20136 at Tecnol\u00f3gico de Monterrey\u2019s Monterrey campus. The event brings together researchers from around the world to share advances in <strong>biomaterials, biofabrication, and their applications in medicine and other industries<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This marks the first time the conference, organized by the International Society for Biofabrication (ISBF), has been held in Latin America. Grissel Trujillo and Mario \u00c1lvarez, researchers at Tec de Monterrey and co-chairs of the conference, emphasized the significance of welcoming this scientific community to Mexico.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cProgress in biofabrication depends not only on scientific excellence, but also on our ability to overcome barriers between disciplines, institutions, and countries,\u201d said J\u00fcrgen Groll, president of the ISBF, during the opening ceremony. \u201cI hope this gathering will advance biofabrication research and foster stronger ties between the ISBF and Latin America.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Were you interested in this story? Do you want to publish it? Contact our content editor to learn more\u00a0<a href=\"mailto:marianaleonm@tec.mx\" target=\"_blank\" rel=\"noopener\">marianaleonm@tec.mx<\/a>.<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Roger Kamm, an MIT researcher, discussed advances in tiny devices that allow scientists to grow human cells under controlled laboratory conditions.<\/p>\n","protected":false},"author":47,"featured_media":174861,"comment_status":"closed","ping_status":"closed","sticky":true,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[93],"tags":[156,596],"class_list":["post-174860","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biotechnology","tag-biotechnology","tag-international-conference-on-biofabrication","sticky"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.0 (Yoast SEO v28.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Using Organs-on-Chips to Understand Cancer and Alzheimer\u2019s | TecScience<\/title>\n<meta name=\"description\" content=\"Roger Kamm, an MIT researcher, discussed the potential of organ-on-a-chip technology to better understand diseases such as cancer and Alzheimer\u2019s.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Recreating Human Blood Vessels on a Chip to Understand Metastasis\" \/>\n<meta property=\"og:description\" content=\"Roger Kamm, an MIT researcher, discussed the potential of organ-on-a-chip technology to better understand diseases such as cancer and Alzheimer\u2019s.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/\" \/>\n<meta property=\"og:site_name\" content=\"TecScience\" \/>\n<meta property=\"article:published_time\" content=\"2026-11-04T22:04:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-05T17:31:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/organs-on-chip-vessels.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"750\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ricardo Trevi\u00f1o\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ricardo Trevi\u00f1o\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/\"},\"author\":{\"name\":\"Ricardo Trevi\u00f1o\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#\\\/schema\\\/person\\\/921fb2c09983802d757dd7aa3cbd2ef9\"},\"headline\":\"Recreating Human Blood Vessels on a Chip to Understand Metastasis\",\"datePublished\":\"2026-11-04T22:04:10+00:00\",\"dateModified\":\"2026-11-05T17:31:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/\"},\"wordCount\":1136,\"publisher\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2026\\\/11\\\/organs-on-chip-vessels.jpg\",\"keywords\":[\"biotechnology\",\"International Conference on Biofabrication\"],\"articleSection\":[\"Biotechnology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/\",\"url\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/\",\"name\":\"Using Organs-on-Chips to Understand Cancer and Alzheimer\u2019s | TecScience\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2026\\\/11\\\/organs-on-chip-vessels.jpg\",\"datePublished\":\"2026-11-04T22:04:10+00:00\",\"dateModified\":\"2026-11-05T17:31:29+00:00\",\"description\":\"Roger Kamm, an MIT researcher, discussed the potential of organ-on-a-chip technology to better understand diseases such as cancer and Alzheimer\u2019s.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#primaryimage\",\"url\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2026\\\/11\\\/organs-on-chip-vessels.jpg\",\"contentUrl\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2026\\\/11\\\/organs-on-chip-vessels.jpg\",\"width\":750,\"height\":500,\"caption\":\"Researchers are studying how tumor cells enter blood vessels, travel through the bloodstream, and cross vessel walls to reach other tissues. (Photo: Getty Images)\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/biotechnology\\\/organs-on-chips-to-understand-cancer-and-alzheimers\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Recreating Human Blood Vessels on a Chip to Understand Metastasis\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/\",\"name\":\"TecScience\",\"description\":\"-\",\"publisher\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#organization\",\"name\":\"TecScience\",\"url\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2022\\\/11\\\/logo-negro-tecscience.svg\",\"contentUrl\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2022\\\/11\\\/logo-negro-tecscience.svg\",\"width\":250,\"height\":38,\"caption\":\"TecScience\"},\"image\":{\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/#\\\/schema\\\/person\\\/921fb2c09983802d757dd7aa3cbd2ef9\",\"name\":\"Ricardo Trevi\u00f1o\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/4bcc2569d80f3bc04d35c88e014da852d10420f44fbbf0158af3ce158042ba08?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/4bcc2569d80f3bc04d35c88e014da852d10420f44fbbf0158af3ce158042ba08?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/4bcc2569d80f3bc04d35c88e014da852d10420f44fbbf0158af3ce158042ba08?s=96&d=mm&r=g\",\"caption\":\"Ricardo Trevi\u00f1o\"},\"url\":\"https:\\\/\\\/tecscience.tec.mx\\\/en\\\/author\\\/rtrevino\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Using Organs-on-Chips to Understand Cancer and Alzheimer\u2019s | TecScience","description":"Roger Kamm, an MIT researcher, discussed the potential of organ-on-a-chip technology to better understand diseases such as cancer and Alzheimer\u2019s.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/","og_locale":"en_US","og_type":"article","og_title":"Recreating Human Blood Vessels on a Chip to Understand Metastasis","og_description":"Roger Kamm, an MIT researcher, discussed the potential of organ-on-a-chip technology to better understand diseases such as cancer and Alzheimer\u2019s.","og_url":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/","og_site_name":"TecScience","article_published_time":"2026-11-04T22:04:10+00:00","article_modified_time":"2026-11-05T17:31:29+00:00","og_image":[{"width":750,"height":500,"url":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/organs-on-chip-vessels.jpg","type":"image\/jpeg"}],"author":"Ricardo Trevi\u00f1o","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Ricardo Trevi\u00f1o","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#article","isPartOf":{"@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/"},"author":{"name":"Ricardo Trevi\u00f1o","@id":"https:\/\/tecscience.tec.mx\/en\/#\/schema\/person\/921fb2c09983802d757dd7aa3cbd2ef9"},"headline":"Recreating Human Blood Vessels on a Chip to Understand Metastasis","datePublished":"2026-11-04T22:04:10+00:00","dateModified":"2026-11-05T17:31:29+00:00","mainEntityOfPage":{"@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/"},"wordCount":1136,"publisher":{"@id":"https:\/\/tecscience.tec.mx\/en\/#organization"},"image":{"@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#primaryimage"},"thumbnailUrl":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/organs-on-chip-vessels.jpg","keywords":["biotechnology","International Conference on Biofabrication"],"articleSection":["Biotechnology"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/","url":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/","name":"Using Organs-on-Chips to Understand Cancer and Alzheimer\u2019s | TecScience","isPartOf":{"@id":"https:\/\/tecscience.tec.mx\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#primaryimage"},"image":{"@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#primaryimage"},"thumbnailUrl":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/organs-on-chip-vessels.jpg","datePublished":"2026-11-04T22:04:10+00:00","dateModified":"2026-11-05T17:31:29+00:00","description":"Roger Kamm, an MIT researcher, discussed the potential of organ-on-a-chip technology to better understand diseases such as cancer and Alzheimer\u2019s.","breadcrumb":{"@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#primaryimage","url":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/organs-on-chip-vessels.jpg","contentUrl":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2026\/11\/organs-on-chip-vessels.jpg","width":750,"height":500,"caption":"Researchers are studying how tumor cells enter blood vessels, travel through the bloodstream, and cross vessel walls to reach other tissues. (Photo: Getty Images)"},{"@type":"BreadcrumbList","@id":"https:\/\/tecscience.tec.mx\/en\/biotechnology\/organs-on-chips-to-understand-cancer-and-alzheimers\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/tecscience.tec.mx\/en\/"},{"@type":"ListItem","position":2,"name":"Recreating Human Blood Vessels on a Chip to Understand Metastasis"}]},{"@type":"WebSite","@id":"https:\/\/tecscience.tec.mx\/en\/#website","url":"https:\/\/tecscience.tec.mx\/en\/","name":"TecScience","description":"-","publisher":{"@id":"https:\/\/tecscience.tec.mx\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/tecscience.tec.mx\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/tecscience.tec.mx\/en\/#organization","name":"TecScience","url":"https:\/\/tecscience.tec.mx\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/tecscience.tec.mx\/en\/#\/schema\/logo\/image\/","url":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2022\/11\/logo-negro-tecscience.svg","contentUrl":"https:\/\/tecscience.tec.mx\/en\/wp-content\/uploads\/sites\/9\/2022\/11\/logo-negro-tecscience.svg","width":250,"height":38,"caption":"TecScience"},"image":{"@id":"https:\/\/tecscience.tec.mx\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/tecscience.tec.mx\/en\/#\/schema\/person\/921fb2c09983802d757dd7aa3cbd2ef9","name":"Ricardo Trevi\u00f1o","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/4bcc2569d80f3bc04d35c88e014da852d10420f44fbbf0158af3ce158042ba08?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/4bcc2569d80f3bc04d35c88e014da852d10420f44fbbf0158af3ce158042ba08?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/4bcc2569d80f3bc04d35c88e014da852d10420f44fbbf0158af3ce158042ba08?s=96&d=mm&r=g","caption":"Ricardo Trevi\u00f1o"},"url":"https:\/\/tecscience.tec.mx\/en\/author\/rtrevino\/"}]}},"_links":{"self":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts\/174860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/users\/47"}],"replies":[{"embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/comments?post=174860"}],"version-history":[{"count":3,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts\/174860\/revisions"}],"predecessor-version":[{"id":174874,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/posts\/174860\/revisions\/174874"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/media\/174861"}],"wp:attachment":[{"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/media?parent=174860"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/categories?post=174860"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tecscience.tec.mx\/en\/wp-json\/wp\/v2\/tags?post=174860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}